A layer’s blend mode decides how it combines with the composite underneath it. The list in the Layers panel is banded by family, and the bands are worth learning: everything in darken can only darken, everything in lighten can only lighten, and everything in contrast pivots around mid-grey.

Normal

Mode What it does
Normal Replaces what is underneath, scaled by opacity. The default.
Pass Through Groups only. The layers inside composite as if the group were not there.

Darken

Every mode here leaves white unchanged and can only make the result darker.

Mode What it does
Darken Takes the darker of the two, channel by channel.
Multiply Multiplies the two. The workhorse for shadows and for putting ink on paper.
Color Burn Darkens by increasing contrast, crushing the shadows.
Linear Burn Darkens by subtracting brightness. Flatter than Color Burn.
Darker Color Takes the darker of the two pixels, judged by luminosity, rather than working channel by channel.

Lighten

The mirror of darken: black is unchanged and the result can only get lighter.

Mode What it does
Lighten Takes the lighter of the two, channel by channel.
Screen The inverse of Multiply. The workhorse for glows and highlights.
Color Dodge Brightens by decreasing contrast, blowing out the highlights.
Linear Dodge (Add) Brightens by adding. What light actually does.
Lighter Color Takes the lighter of the two pixels by luminosity.

Contrast

These pivot around mid-grey: 50% grey leaves the backdrop unchanged, darker values darken and lighter values lighten.

Mode What it does
Overlay Multiply on the dark half, Screen on the light half, judged by the backdrop.
Soft Light A gentler Overlay. The usual choice for dodging and burning on a grey layer.
Hard Light Overlay judged by the layer instead of the backdrop.
Vivid Light Color Burn below mid-grey, Color Dodge above. Strong.
Linear Light Linear Burn below, Linear Dodge above.
Pin Light Replaces values rather than blending them; useful for special effects, harsh for photographs.
Hard Mix Pushes every channel to 0 or 255. Posterizes hard.

Compare

Mode What it does
Difference The absolute difference between the two. Two identical layers give black — which is how you check whether they are identical.
Exclusion A lower-contrast Difference.
Subtract Subtracts the layer from the backdrop.
Divide Divides the backdrop by the layer.

Component

These four take part of the colour from the layer and the rest from the backdrop. They are defined on whole pixels rather than per channel, so they have no channel-by-channel form.

Mode Takes from the layer Takes from the backdrop
Hue Hue Saturation and luminosity
Saturation Saturation Hue and luminosity
Color Hue and saturation Luminosity
Luminosity Luminosity Hue and saturation

Color on a layer of flat paint is how you tint a photograph without touching its tones. Luminosity on a sharpened copy is how you sharpen detail without shifting colour.

Which ones are separable

A separable mode computes each of red, green and blue independently. Twenty-two of the twenty-eight are. The six that are not — Hue, Saturation, Color, Luminosity, Darker Color and Lighter Color — are defined on the pixel as a whole, which is why they cannot be applied one channel at a time.

Opacity and fill

The blend runs first, then opacity scales the result against the backdrop. A layer at 50% Multiply is halfway between the multiplied result and the original — not a multiply by a half-strength layer.